Respiratory distress following major trauma: Predictive value of blood coagulation tests

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Coagulation complications following trauma

Traumatic injury is one of the leading causes of death, with uncontrolled hemorrhage from coagulation dysfunction as one of the main potentially preventable causes of the mortality. Hypothermia, acidosis, and resuscitative hemodilution have been considered as the significant contributors to coagulation manifestations following trauma, known as the lethal triad. Over the past decade, clinical ob...

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[Coagulation management in major trauma].

In trauma associated coagulopathy, the initial treatment consists of hypothermia and acidosis have to be treated aggressively. Already in in the emergency room, fibrinogen deficiency can be detected frequently, in addition, colloids interfere with fibrin polymerisation. Under these aspects, the early administration of fibrinogen seems to be justified. Depleted coagulation factors can be substit...

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Coagulation management in major trauma

Bleeding is a common problem in major trauma. Coagulopathy could be detected in approximately 25% of all trauma patients on arrival in the emergency room. The reasons for that are blood loss, dilution of the remaining coagulation factors by fluids not containing coagulation factors, consumption of coagulation factors and hyperfibrinolysis. Hypothermia and acidosis are also well described contri...

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Respiratory distress following pneumonectomy.

A 60-year-old man was referred to the thoracic surgery service with a large mass in the right upper lobe of his lung. He had a 4-week history of productive cough and hemoptysis. A chest radiograph was obtained after antibiotic therapy failed to resolve the symptoms. He had no history of weight loss, fevers, or chest pain. He had smoked until 2 years prior and had an 80 pack-year history of ciga...

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Blood and coagulation support in trauma care.

Injuries are common and account for almost 15% of all blood use in the U.S. The historic view that the coagulopathy associated with severe injury was largely dilutional is being replaced by epidemiologic and molecular evidence for a distinct syndrome of trauma-associated coagulopathy. This coagulopathy of trauma is the sum of the effects of blood loss and dilution, coagulation factor and platel...

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ژورنال

عنوان ژورنال: Acta Orthopaedica Scandinavica

سال: 1986

ISSN: 0001-6470

DOI: 10.3109/17453678609000892